Tesamorelin and Ipamorelin are growth hormone secretagogues studied for their combined potential to enhance GH release and support metabolic signaling pathways. Tesamorelin acts as a GHRH analog, while Ipamorelin stimulates the ghrelin receptor, promoting natural GH pulsatility. Research focuses on how their dual mechanism may influence fat metabolism, recovery, and endocrine regulation in preclinical models.